Sedating antihistimine constipation
Other brands of promethazine include Sominex and Avomine.
Your doctor may also prescribe promethazine as unbranded or generic tablets and it may be given by injection in hospital.
Phenergan is a brand name for an antihistamine called promethazine hydrochloride.
This medicine has lots of different uses, including treating allergies and travel sickness.
They act on histamine receptors in the brain and spinal cord and in the rest of the body (called the periphery).
They also act on muscarinic, alpha-adrenergic, and serotonin receptors.
Histamine-1 receptors are also found in the brain and spinal cord, and stimulation of these receptors makes you more awake and alert.For travel sickness: Promethazine also blocks histamine receptors in an area of the brain called the vomiting centre.This part of the brain is activated when it gets nerve messages from a part of the inner ear called the vestibular apparatus.It's responsible for making you feel sick and for the vomiting reflex.Promethazine stops the vomiting centre being activated.