After the region's conquest by Alexander the Great it became part of the Greco-Bactrian Kingdom, a successor state of Alexander's empire.
Northern Tajikistan (the cities of Khujand and Panjakent) was part of Sogdia, a collection of city-states which was overrun by Scythians and Yuezhi nomadic tribes around 150 BCE.
The Silk Road passed through the region and following the expedition of Chinese explorer Zhang Qian during the reign of Wudi (141–87 BCE) commercial relations between Han China and Sogdiana flourished.
The Kushan Empire, a collection of Yuezhi tribes, took control of the region in the first century CE and ruled until the 4th century CE during which time Buddhism, Nestorian Christianity, Zoroastrianism, and Manichaeism were all practised in the region.
Cultures in the region have been dated back to at least the 4th millennium BCE, including the Bronze Age Bactria–Margiana Archaeological Complex, the Andronovo cultures and the pro-urban site of Sarazm, a UNESCO World Heritage site.
Some authors have also suggested that in the 7th and 6th century BCE parts of modern Tajikistan, including territories in the Zeravshan valley, formed part of Kambojas before it became part of the Achaemenid Empire.
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It is bordered by Afghanistan to the south, Uzbekistan to the west, Kyrgyzstan to the north, and China to the east.
The Emirate of Bukhara remained intact until the 20th century but during the 19th century, for the second time in world history, a European power (the Russian Empire) began to conquer parts of the region.On 9 September 1991, Tajikistan became an independent sovereign nation when the Soviet Union disintegrated.A civil war was fought almost immediately after independence, lasting from 1992 to 1997.Although the Jadidists were pro-modernization and not necessarily anti-Russian, the Russians viewed the movement as a threat.Russian troops were required to restore order during uprisings against the Khanate of Kokand between 19.